Enfamil Gentlease Vs. Similac Pro-Sensitive – What’s The Difference?

Enfamil vs Similac

Enfamil vs Similac, which one is better? An image of milk inside a scoop.
Source: publicdomainpictures.net



  • A different Enfamil Gentlease formula may have side effects compared to regular Similac or Enfamil formulas or well-known formula brands like Enfamil Gentlease. That is where the Similac Gentlease debate comes in, which a lot of parents prefer.
  • In the article, we will compare Enfamil gentlease versus Similac and see if which one is the best. Learn more about these brands including Similac.

When choosing an exclusive blend of sensitive infant formula that will help your child’s gut health as well, you usually have two options: Enfamil Gentlease and Similac Sensitive. Both of these best sensitive baby formula options are some of the top-sensitive formula-based choices for the baby’s tummy.

They are good for a child, and both are good options.

Here, we’ll discuss Similac Sensitive versus Enfamil Gentlease, and whether or not they will help your child achieve complete nutrition, acquire vitamin D and other nutrients, good calcium absorption, and digestive health. We want to know the best baby formula for breastfed babies as well. The following are some of the things you can learn in this article:

  • Enfamil vs Similac comparison
  • Enfamil and Similac review
  • Enfamil and Similac difference
  • Enfamil and Similac similarities

Enfamil vs Other Brands

Comparing Key Ingredients: Breast Milk, Corn Syrup Solids, And Partially Hydrolyzed Nonfat Milk In Formulas

  • Similac Sensitive offers a formula specifically formulated to help babies with digestive issues and provide complete nutrition. This makes it a suitable choice for parents exploring a new formula in the Similac product line, such as Similac Pro Total Comfort.
  • Similac contains coconut oil, high Similac oleic safflower oil, and Similac soy oil. Enfamil, their top competitor, released a similar formula, Enfamil Gentlease. Enfamil Gentlease and the other comes with their good and bad things, hence parents should be aware. Similac is for sensitive babies.

    Enfamil vs Similac - Enfamil Neuro Pro Gentlease Infant Formula-one of the best proven formula milk for your baby
    Source: flickr.com

Every Enfamil and Similac comes with a list of potential side effects, and parents often need to find out how it will affect their baby by trial and error or by reading reviews from other parents who have chosen their own formula. Often, these are listed on the side of the can. These are the most common side effects of both brands and the other.

Similac Sensitive Formulas

Common side effects include:

  1. Fussiness with Similac
  2. Similac: Gas
  3. Constipation Increased spit up upon Smilac intake

Enfamil Gentlease

Common side effects include:

  1. Diarrhea after taking Enfamil
  2. Enfamil: Explosive diarrhea
  3. Increased spit up after Enfamil intake
  4. Increased fuziness with Enfamil
  5. Irritation with Enfamil

Enfamil Gentlease versus Similac Sensitive Version Results On Baby’s Digestive System

When you buy Enfamil Gentlease, you’re searching for a formula that will help with your baby’s digestive problems, whether that is constipation, gas, mild spit-up, or difficulty digesting lactose. These are the most common results that other parents posted in their reviews.

Similac Sensitive Formulas

When you switch to Similac Sensitive, you won’t have to worry about diarrhea as much, but it seems to be common for babies to spit up more, sometimes with every bottle. On the flip side, you might have to worry about constipation or gas, the very things that Enfamil Gentlease is supposed to prevent. Most parents can safely make the switch, though, and you can see positive results like less fussiness within a day of fully making the switch. This also contains the prebiotic 2 FL HMO (human milk oligosaccharides) for a stronger immune system. Similac claims its spit-up formula reduces spit-up episodes in babies. Similac is good for premature babies as they support the healthy growth of babies.

Sensitive, best for your baby
Source: flickr.com

Enfamil Gentlease

Most parents are a bit disappointed by explosive diarrhea, but it’s not usually bad enough that you are going to have to worry about your little one becoming dehydrated. Despite this, most moms are reporting that their babies are happier on Enfamil Gentlease than on other formulas. Through regular and frequent feedings, you can see a decrease in fussiness within a few days, and many parents believe that this is the only Enfamil for their little ones.

  • Enfamil Gentlease is one of the few formulas with a partially hydrolyzed whey protein.
  • Enfamil Gentlease infant formula contains Enfamil vegetable oils, high enfamil oleic sunflower oils, and broken-down lactose proteins.

Partially hydrolyzed nonfat milk is a type of partially hydrolyzed option and partially hydrolyzed nonfat milk is something that makes it similar to cow’s milk. The one downside to partially hydrolyzed nonfat milk in a formula is for those who are allergic or have a reaction to milk or protein, they can’t have partially hydrolyzed nonfat milk since it will cause the allergy to flare up in many cases.

Price Of Enfamil Gentlease versus Sensitive Version

Both of these are popular baby formula brands, so you can expect them to be pricier than the store brand, but it’s always important to compare costs so that you get a formula that is right for both your baby and your bank account. TIP: Buying in bulk is an awesome way to save money if either of these seems to be out of your budget. There are many quality baby formula brands you can choose from.

Price does vary depending on several factors, such as whether you’re opting for powdered formula or readymade formula. As a general rule of thumb, Enfamil is cheaper than Similac in almost every scenario.

Like Enfamil, this brand also has many versions
Source: flickr.com

Gentlease versus Similac sensitive Version Availability

Sometimes, a formula is not as readily available as you wish it was. For example, my grandson has to have Similac Neosure because he was born five weeks early. He also has a prescription for it. Unfortunately, most people in my city are on WIC, which has a contract with Gerber. That means that a lot of the stores around me don’t carry the Neosure. I’m stuck getting it at two stores or going out of town. Making sure that your choice is available nearby or online is a necessity.

It’s also important to make sure that the formula is available in your preference, like ready-made bottles, powder, or milk proteins for babies that are sensitive to milk. You can buy milk from the following sources:

  • Enfamil & Similac online
  • Enfamil & Similac local stores
  • Enfamil & Similac at Walmart

Similac Sensitive

With the formula Similac Sensitive, you will get a milk-based baby formula that is easy to digest and doesn’t contain explosive diarrhea as the Gentlease formula does. This is the best formula for newborns who need something easy to digest, and with a milk protein isolate that is one of the tops on the market. This brand is incorporated with a good amount of fat protein blend essential for a child’s brain development. Similac has reduced quantities of docosahexaenoic acid (DHA) for lower fat levels.

  • Similac contains the A2 milk protein, which is a Similac milk protein isolate not found in any other baby formula. The Similac Pro Sensitive Advance offers immune support in the Similac milk protein.
  • The Enfamil Gentlease Pro Advance vs Similac has a milk protein isolate that is not made with artificial flavors, perfect for sensitive stomachs.
  • The Enfamil Pro Sensitive vs Similac infant formula is similar to the Similac Pro Sensitive Advance in that it has some of the same protein isolate and milk Similac protein contents that the Similac Pro Advance formula does. Similac is the best best baby formula for constipation and sensitive stomachs.
  • You also have Enfamil Total Comfort and Similac, which is the best one for those who want a baby Enfamil formula that contains a protein isolate for digestion.
  • Similac Sensitive is a great milk-based baby formula that will provide a variety of different milk protein compounds that will help the child.
Different milk formula for baby, like Enfamil. Check the things you need to know about these formulas.
Source: commons.wikimedia.org


Enfamil Gentlease can be ordered online and can be found at most major retailers, offering convenience with options like ready to feed bottles. When it comes to variety, it takes the cake. It can be found in single-serving packets, ready-to-eat bottles, powdered formula, bulk cans of powder, and already-made canisters. It even has a liquid form you can buy.

If you have a preference, this one has got you covered.  It is similar to Similac formulas, but it also offers a baby formula with a milk protein and a milk protein isolate that is easy to digest.

It is the best formula for baby option because this milk-based formula with fat protein blend is easy to digest, and offers a lot of options. The Beauty of this formula is that with this, you’ll get a variety of baby formula options to help your child. Whether you want something similar to human milk or with a milk protein isolate that works for them, this is one of the best for you to consider.

Enfamil Enspire

While the formula is one of the easiest infant formulas for the stomach, Enfamil Enspire is the closest you will get to human breast milk. This is great for children who are weaning off breast milk because this brand contains milk and whey protein concentrate solids in this baby formula that will help the child get all the vitamins and minerals that they might get out of breast milk. These are great products to use for your baby before they start to eat solid food.

For some infant formula, especially milk-based infant formula, you want something similar to breast milk, and luckily, it offers that.  It also contains a milk-based protein that is commonly found in breast milk, which is designed to not only help with brain development but also offer the same nourishments that you will get in breast milk.

With the Enspire variations, you’ll be able to offer breast milk benefits without breast milk, and the traditional milk protein formula within this brand offers significant healthy growth, and it is easy to digest.

This is the best baby formula for those looking for something easy to digest but also is similar to breast milk in terms of milk-based protein options. Enfamil Enpsire is an infant formula made to provide similar nutrients that breast milk does but is also a baby food that will give children everything they need.

Enfamil - Enfamil Gentlease Enspire for easing gas, fussiness and crying
Source: flickr.com

Enfamil Neuropro Gentlease

As a bonus, this is also available in Neuropro form. This gentle milk powder formula has all the vitamins (like vitamin E, k, and B2), fat protein blend mfgm, and nutrients that are commonly found in breast milk. According to the advertisements, it can reduce fussiness and gas in a quick 24 hours. According to customer reviews, it works most of the time. It does come with the same side effect of explosive diarrhea, though.

  • Enfamil Neuropro vs Similac is great for babies with sensitive stomachs, as it contains a unique blend of other essential nutrients to support their overall development, and many parents like Enfamil Neuropro because not only does it help with sensitive tummies, but also offers a simple formula to build cognitive and brain development.
  • Enfamil Neuropro infant formula vs Similac does contain a protein isolate in there, and it can sometimes create diarrhea in the baby. But it is a baby formula that’s similar to breast milk, and this protein isolate can help build development.
  • Some people like the Neuropro infant formula because the milk protein in it will help with improving the baby’s cognitive development. Enfamil Nutramigen baby formula is suited for an infant who has a cow’s milk protein allergy.
  • A cow’s milk protein allergy is an allergy caused by a reaction in cow’s milk, in cases such as these, you opt to buy a gentler formula out there. This formula is also good for those who are lactose intolerant since it is hypoallergenic and lactose-free at the same time. If you’re looking for reduced lactose formulas out there, then search no more.
  • There are many formulas out there that can help with a gassy baby differently, such as reduced lactose formulas that contain essential fatty acids from vegetable oil. When choosing a baby’s formula, it’s important to consider their individual needs and consult with a pediatrician if necessary.
Enfamil - Enfamil Neuropro Infant Formula
Source: flickr.com


Both milk brands are excellent options for infant formula, and parents may choose based on their baby’s specific needs. Each brand offers a unique blend of nutrients, including DHA and other essential nutrients, to support brain health and overall development. They provide quality baby formula to meet these needs. Finding a store that carries these products is relatively easy, and both brands even offer gift cards and vouchers for those looking to save money on infant formula.

  • Similac supports nutrition
  • Similac helps brain development
  • Similac is gentle
  • Similac is  a lactose-free option
  • Similac has prebiotics

Whichever formula you choose for your baby, just remember to never let him drink soft drinks!

Frequently Asked Questions (FAQs)

What Is The Gentlease Formula Used For?

This formula is used to reduce fussiness, gas, and other symptoms of an upset stomach in infants.

Tummy aches might be caused by natural sugar lactose. Gentelease is said to be good for those who have lactose sensitivity because these products do not have high fructose corn syrup (HFCS). Instead of using high fructose corn syrup as a source of carbohydrates, it uses corn syrup solids instead.

Keep in mind that corn syrup solids are not the same as HFCS. Corn syrup is believed to be an essential source of energy which is why infant formulas make use of corn syrup solids. Corn syrup solids are recognized as safe by the FDA, the concept that corn syrup is harmful is only a myth.

Make sure to consult a pediatrician for clarification if your baby has lactose sensitivity.

Enfamil VS Similac: What Formula Is Easiest On The Baby’s Stomach?

The first one is the easiest formula for babies. It doesn’t cause diarrhea, parents report that their babies are still happy and they do not cry as much, leading us to believe that it’s easier on the baby’s stomach.

On the other hand, Similac for Spit-Up is good for babies with acid reflux.

Enfamil - Enfamil is pretty easy on the stomach for babies
Source: pikrepo.com

Enfamil Vs Similac: Which Is Easier To Digest?

Both of them are easy to digest due to the ingredient that is called corn syrup. Both milk brands have corn syrup in their baby formulas. It is not a myth that ithas corn syrup solids, Enfamil formulas, have a type of corn syrup starch that is known for making them easier to digest than other formulas.

Similac Pro-Sensitive Infant Formula
Source: flickr.com

Corn syrup solids are believed to be safe (corn syrup harmful is only a myth) and approved by the FDA which is why both of these brands have it. However, this can cause an upset stomach in some babies. Consult a pediatrician if you think corn syrup harms your baby.

What Formula Do Hospitals Use For Babies?

  • Similac is the leading infant formula brand that most hospitals recommend to be used. Similac is also among the hypoallergenic baby formula brands out there. Similac and Enfamil baby formula belongs to organic formulas which are clinically proven to cover all of your baby’s needs. Similac and Enfamil, both are okay.

Which Type Of Enfamil Is Best?

  • The best choice would be the Enfamil NeuroPro. Enfamil over Similac has a total of 30 nutrients to help support your baby’s body and overall development. Enfamil over Similac is great.

Is Gentlease FDA-approved?

Yes, it is. The World Health Organization’s recommended amount of DHA is 0.2% and the NeuroPro offers that. This addresses feeding needs like tummy troubles and spit-up Similac. It also has corn maltodextrin. All of the products have met or exceeded FDA standards.

Why Is Enfamil So Foamy?

Which Formula Is Closest To Breast Milk?

Can I Mix Similac Pro Sensitive And Enfamil?

Does This Brand Cause Constipation?

Is Gentlease Cow Milk-Based?

Similac Or Enfamil: Which Is Better?

Is It OK To Switch From Similac To Enfamil?

What Is The Generic Brand For Enfamil?

Which Similac Formulas Are Similar To Enfamil?


Enfamil Gentlease And Similac Version Other Resources


Last Updated on May 14, 2023 by Mary Cimeni

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